目錄:愛(ài)必信（上海）生物科技有限公司>>生化試劑>>小分子化合物>> abs47027261Brivudine 69304-47-8
| 參考價(jià) | ￥353-￥669 |
參考價(jià)：￥353 ~ ￥669
5mg 10mg 25mg >
CAS:69304-47-8 純度:99% 分子量:333.14 分子式:C11H13BrN2O5 供貨周期:現(xiàn)貨 規(guī)格:5mg 貨號(hào):abs47027261 應(yīng)用領(lǐng)域:化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 主要用途:used in the treatment of herpes zoster
>| 5mg | 353元 | 999mg可售 |
| 10mg | 441元 | 999mg可售 |
| 25mg | 546元 | 999mg可售 |
更新時(shí)間：2025-12-04 10:21:05瀏覽次數(shù)：738評(píng)價(jià)
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| CAS | 69304-47-8 | 純度 | 99% |
|---|---|---|---|
| 分子量 | 333.14 | 分子式 | C11H13BrN2O5 |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 5mg |
| 貨號(hào) | abs47027261 | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
| 主要用途 | used in the treatment of herpes zoster |
Brivudine 69304-47-8
| 產(chǎn)品描述 | |
| 描述 | Brivudine is an antiviral drug used in the treatment of herpes zoster. |
| 純度 | 99% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 溴fu定；溴比夫定； Bromovinyldeoxyuridine；BVDU |
| 外觀 | 白色至淡黃色結(jié)晶性粉末 |
| 可溶性/溶解性 | DMSO : ≥330 mg/mL |
| 生物活性 | |
| 靶點(diǎn) | CMV |
| In vitro(體外研究) | Brivudine is an analog of thymidine, and is incorporated into the viral DNA. It blocks the action of DNA polymerases, thus inhibiting viral replication. It has a stronger antiviral effect against the varicella-zoster virus compared with reference compounds such as aciclovir or penciclovir. It has high, selective activity against varicella zoster virus (VZV), inhibiting VZV replication, possibly through competitive inhibition of viral DNA polymerase, or by acting as an alternative substrate to deoxythymidine triphosphate, causing viral DNA strand breakage. |
| In vivo(體內(nèi)研究) | At a dose of 125 mg once daily, brivudine has proved to be superior to aciclovir with respect to reducing the period of new blister production, and has shortened the duration of post-herpetic neuralgia. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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