目錄:愛(ài)必信（上海）生物科技有限公司>>生化試劑>>小分子化合物>> abs47028212Xanthurenic Acid 59-00-7
| 參考價(jià) | ￥481-￥3518 |
參考價(jià)：￥481 ~ ￥3518
5mg 10mg 20mg >
CAS:59-00-7 純度:98% 分子量:205.17 分子式:C10H7NO4 供貨周期:現(xiàn)貨 規(guī)格:5mg 貨號(hào):abs47028212 應(yīng)用領(lǐng)域:化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 主要用途:is a chemical
>| 5mg | 481元 | 999mg可售 |
| 10mg | 849元 | 999mg可售 |
| 20mg | 1335元 | 999mg可售 |
更新時(shí)間：2026-01-23 13:39:09瀏覽次數(shù)：798評(píng)價(jià)
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| CAS | 59-00-7 | 純度 | 98% |
|---|---|---|---|
| 分子量 | 205.17 | 分子式 | C10H7NO4 |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 5mg |
| 貨號(hào) | abs47028212 | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
| 主要用途 | is a chemical |
Xanthurenic Acid 59-00-7
| 產(chǎn)品描述 | |
| 描述 | Xanthurenic acid, or xanthurenate, is a chemical shown to induce gametogenesis of Plasmodium falciparum, the parasite that causes malaria. It is found in the gut of the Anopheles mosquito. Xanthurenic acid is a metabolic intermediate that accumulates and is excreted by pyridoxine (vitamin B6) deficient animals after the ingestion of tryptophan. |
| 純度 | 98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 4,8-二羥基喹啉-2-甲酸；黃尿酸 |
| 外觀 | Yellow to brown powder |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| 靶點(diǎn) | mGlu2 ,mGlu3 |
| In vitro(體外研究) | Xanthurenic acid (XA) is considered as a putative neurotransmitter in the CNS, being stored in synaptic vesicles and released by membrane depolarization in a Ca2+-dependent fashion. It is known to inhibit vesicular glutamate transporters (VGLUTs). In heterologous expression systems, Xanthurenic acid could activate both mGlu2 and mGlu3 receptors with high potency, but has no activity on mGlu4 and mGlu7 receptors. Xanthurenic acid induces cell death associated with caspase-3, -8, and -9 activation, nuclear DNA cleavage, and cytochrome C release while not associated with cytoskeleton breakdown -- apoptosis induced by xanthurenic acid does not cause cytoskeleton depolymerization. |
| In vivo(體內(nèi)研究) | Systemic administration of Xanthurenic acid in mice produces antipsychotic-like effects in the MK-801-induced model of hyperactivity and peripheral xanthurenic acid can cross the blood-brain barrier, influence the activity of brain regions that are involved in the pathophysiology of schizophrenia. |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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