目錄:愛(ài)必信（上海）生物科技有限公司>>生化試劑>>小分子化合物>> abs47028416Z-FA-FMK 197855-65-5
| 參考價(jià) | ￥2455-￥7165 |
參考價(jià)：￥2455 ~ ￥7165
10mg 50mg
CAS:197855-65-5 純度:＞98% 分子量:386.42 分子式:C21H23FN2O4 供貨周期:現(xiàn)貨 規(guī)格:10mg 貨號(hào):abs47028416 應(yīng)用領(lǐng)域:化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 主要用途:is an irreversible cysteine protease in
>| 10mg | 2455元 | 999mg可售 |
| 50mg | 7165元 | 999mg可售 |
更新時(shí)間：2026-02-03 13:32:55瀏覽次數(shù)：959評(píng)價(jià)
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| CAS | 197855-65-5 | 純度 | ＞98% |
|---|---|---|---|
| 分子量 | 386.42 | 分子式 | C21H23FN2O4 |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10mg |
| 貨號(hào) | abs47028416 | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
| 主要用途 | is an irreversible cysteine protease in |
Z-FA-FMK 197855-65-5
| 產(chǎn)品描述 | |
| 描述 | Z-FA-FMK is an irreversible cysteine protease inhibitor, and also inhibits effector caspases. |
| 純度 | ＞98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | Z-Phe-Ala fluoromethyl ketone |
| 外觀 | 白色固體 |
| 可溶性/溶解性 | DMSO : 71 mg/mL (183.7 mM) Ethanol : 32 mg/mL (82.8 mM) |
| 生物活性 | |
| 靶點(diǎn) | cysteine protease |
| In vitro(體外研究) | Z-FA-FMK inhibits the degradation of fibrillar collagen by fibroblasts and osteoclasts. Z-FA-FMK inhibits LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Z-FA-FMK efficiently blocks T cell proliferation induced by mitogens and IL-2 in vitro. |
| In vivo(體內(nèi)研究) | Z-FA-FMK significantly increases pneumococcal growth in both lungs and blood in a mouse model of intranasal pneumococcal infection. Z-FA-FMK blocks reovirus infection of Ras oncogenic tumours and host heart tissues in severe combined immunodeficiency mice. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | CancerInvasion/microenvironmentAngiogenesisECM enzymesCathespins CancerInvasion/microenvironmentECMCell adhesionOther CancerInvasion/microenvironmentECMExtracellular matrixOther NeuroscienceProcesses NeuroscienceCell Adhesion ProteinsMembrane Proteins Signal TransductionCytoskeleton / ECMExtracellular MatrixOther EnzymesECM Enzymes Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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