Interleukin 22 （IL-22） is an α-helical cytokine, predicts a molecular mass of 16.9 kDa. It is produced by T-helper （Th）-17 cells, γδ T cells, NKT cells and newly described innate lymphoid cells （ILCs）. Effects involve stimulation of cell survival, proliferation and synthesis of antimicrobials including S110, Reg3β, Reg3γ and defensins.
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