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IntroductionNearly two decades ago, Gibco™ CTS™ Dynabeads™ CD3/CD28technology was used in the first pioneering, clinically approvedCAR T cell therapy [1]. The antibody-coated magnetic beadswere crucial in the manufacturing process to achieve one-stepcell isolation and activation, and enabled clinical-scale doseproduction within 2 to 3 weeks. Since then, the technology hasbecome well established in the industry and has been used inover 200 clinical trials to provide critically needed treatment forpatients

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