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Transfer of a Chinese and U.S. Pharmacopeia method for furosemide from an Agilent 1220 Infinity LC s

閱讀：331 發(fā)布時間：2025-08-06

Application benefits

The Thermo Scientific" Vanquish" Access HPLC system combined with a Thermo Scientific" Hypersil GOLD" column can easily reproduce the pharmacopeia method for furosemide assay and impurity.

Thermo Scientific" Chromeleon" Chromatography Data System (CDS) enables flawless control of multi-vendor LC systems in one software and provides interactive visualization tools for method lifetime monitoring.

Goals

To highlight the seamless method transfer from an Agilent" 1220 Infinity”" LC VL to a Vanquish Access HPLC system by obtaining similar results.

To demonstrate Chromeleon CDS tools for routine use in quality control laboratories.

Introduction

Developing reliable and reproducible quality control methods is a crucial process in pharmaceutical manufacturing to ensure the purity of drugs for their therapeutic substance(s) (content) and safety (impurities). High-performance liquid chromatography

(HPLC) analysis is the prefered technique for measuring drug content and impurities

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Transfer of a Chinese and U.S. Pharmacopeia method for furosemide from an Agilent 1220 Infinity LC s

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